Ramirez, the Central California star, was gearing up to make his first defense against Danny O'Connor in the main event of a Top Rank Boxing on ESPN card on July 7 at the Save Mart Center in Fresno, only to have the fight shockingly canceled on a little more than 24 hours' notice.
But Top Rank quickly rescheduled Ramirez and matched with a far superior opponent in longtime contender Antonio Orozco.
play 0:57 Ramirez 'very disappointed' fight vs. O'Connor is off Jose Ramirez's title bout versus Danny O'Connor has been canceled after O'Connor was hospitalized with dehydration.
Jose Ramirez, left, will have trainer Robert Garcia in his corner for his first junior welterweight title defense on Saturday.
Antonio Orozco, left, will be fighting for his first world title against junior welterweight world belt-holder Jose Ramirez on Saturday.