Santa Cruz is instead defending his WBA super world featherweight title against Chris Avalos, a fighter who is on a rather poor run of form of late.
Mares will be taking on Andres Gutierrez to defend his regular WBA world featherweight title in the co-feature of the PBC on Fox card.
Santa Cruz vs. Avalos Fight Info
Santa Cruz has put together an excellent run over the last couple of years, with Ring rating him the top featherweight in the world.
Santa Cruz came back a few months later in January of this year to face Frampton again, this time coming out on top in yet another majority decision.